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Bilirubin Inhibits Neointima Formation and Vascular Smooth Muscle Cell Proliferation and Migration
Bilirubin is a heme metabolite generated by the concerted action of the enzymes heme oxygenase and biliverdin reductase. Although long considered a toxic byproduct of heme catabolism, recent preclinical, and clinical studies indicate the bilirubin exerts beneficial effects in the circulation. In the...
Autores principales: | Peyton, Kelly J., Shebib, Ahmad R., Azam, Mohammad A., Liu, Xiao-ming, Tulis, David A., Durante, William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309974/ https://www.ncbi.nlm.nih.gov/pubmed/22470341 http://dx.doi.org/10.3389/fphar.2012.00048 |
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