Candida spp. with Acquired Echinocandin Resistance, France, 2004–2010

We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically rela...

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Autores principales: Dannaoui, Eric, Desnos-Ollivier, Marie, Garcia-Hermoso, Dea, Grenouillet, Fredéric, Cassaing, Sophie, Baixench, Marie-Thérèse, Bretagne, Stéphane, Dromer, Françoise, Lortholary, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2012
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310099/
https://www.ncbi.nlm.nih.gov/pubmed/22257484
http://dx.doi.org/10.3201/eid1801.110556
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author Dannaoui, Eric
Desnos-Ollivier, Marie
Garcia-Hermoso, Dea
Grenouillet, Fredéric
Cassaing, Sophie
Baixench, Marie-Thérèse
Bretagne, Stéphane
Dromer, Françoise
Lortholary, Olivier
author_facet Dannaoui, Eric
Desnos-Ollivier, Marie
Garcia-Hermoso, Dea
Grenouillet, Fredéric
Cassaing, Sophie
Baixench, Marie-Thérèse
Bretagne, Stéphane
Dromer, Françoise
Lortholary, Olivier
author_sort Dannaoui, Eric
collection PubMed
description We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.
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spelling pubmed-33100992012-04-10 Candida spp. with Acquired Echinocandin Resistance, France, 2004–2010 Dannaoui, Eric Desnos-Ollivier, Marie Garcia-Hermoso, Dea Grenouillet, Fredéric Cassaing, Sophie Baixench, Marie-Thérèse Bretagne, Stéphane Dromer, Françoise Lortholary, Olivier Emerg Infect Dis Dispatch We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related. Centers for Disease Control and Prevention 2012-01 /pmc/articles/PMC3310099/ /pubmed/22257484 http://dx.doi.org/10.3201/eid1801.110556 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Dannaoui, Eric
Desnos-Ollivier, Marie
Garcia-Hermoso, Dea
Grenouillet, Fredéric
Cassaing, Sophie
Baixench, Marie-Thérèse
Bretagne, Stéphane
Dromer, Françoise
Lortholary, Olivier
Candida spp. with Acquired Echinocandin Resistance, France, 2004–2010
title Candida spp. with Acquired Echinocandin Resistance, France, 2004–2010
title_full Candida spp. with Acquired Echinocandin Resistance, France, 2004–2010
title_fullStr Candida spp. with Acquired Echinocandin Resistance, France, 2004–2010
title_full_unstemmed Candida spp. with Acquired Echinocandin Resistance, France, 2004–2010
title_short Candida spp. with Acquired Echinocandin Resistance, France, 2004–2010
title_sort candida spp. with acquired echinocandin resistance, france, 2004–2010
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310099/
https://www.ncbi.nlm.nih.gov/pubmed/22257484
http://dx.doi.org/10.3201/eid1801.110556
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