Mutations I117V and I117M and Oseltamivir Sensitivity of Pandemic (H1N1) 2009 Viruses

Analysis of mutations I117V and I117M in the neuraminidase of influenza A pandemic (H1N1) 2009 viruses showed that I117V confers a mild reduction in oseltamivir sensitivity and has a synergistic effect of further increasing resistance when combined with H275Y. Contrary to recent reports, the I117M m...

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Detalles Bibliográficos
Autores principales: Hurt, Aeron C., Leang, Sook Kwan, Speers, David J., Barr, Ian G., Maurer-Stroh, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2012
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310118/
https://www.ncbi.nlm.nih.gov/pubmed/22260817
http://dx.doi.org/10.3201/eid1801.111079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310118/
https://www.ncbi.nlm.nih.gov/pubmed/22260817
http://dx.doi.org/10.3201/eid1801.111079

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