Cargando…
Mycobacteria activate γδ T-cell anti-tumour responses via cytokines from type 1 myeloid dendritic cells: a mechanism of action for cancer immunotherapy
Attenuated and heat-killed mycobacteria display demonstrable activity against cancer in the clinic; however, the induced immune response is poorly characterised and potential biomarkers of response ill-defined. We investigated whether three mycobacterial preparations currently used in the clinic (BC...
Autores principales: | Fowler, Daniel W., Copier, John, Wilson, Natalie, Dalgleish, Angus G., Bodman-Smith, Mark D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310139/ https://www.ncbi.nlm.nih.gov/pubmed/22002242 http://dx.doi.org/10.1007/s00262-011-1121-4 |
Ejemplares similares
-
The cytotoxic molecule granulysin is capable of inducing either chemotaxis or fugetaxis in dendritic cells depending on maturation: a role for Vδ2(+)
γδ T cells in the modulation of immune response to tumour?
por: Sparrow, Emma L., et al.
Publicado: (2020) -
Zoledronic acid renders human M1 and M2 macrophages susceptible to Vδ2(+) γδ T cell cytotoxicity in a perforin-dependent manner
por: Fowler, Daniel W., et al.
Publicado: (2017) -
T-regulatory cell modulation: the future of cancer immunotherapy?
por: Nizar, S, et al.
Publicado: (2009) -
Serum Apolipoprotein E and Other Inflammatory Markers Can Identify Non-Responding Patients to a Dendritic Cell Vaccine()()
por: Leeman, Hayley, et al.
Publicado: (2018) -
In vitro culture with gemcitabine augments death receptor and NKG2D ligand expression on tumour cells
por: Gravett, Andrew M., et al.
Publicado: (2019)