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L(+) and D(−) Lactate Are Increased in Plasma and Urine Samples of Type 2 Diabetes as Measured by a Simultaneous Quantification of L(+) and D(−) Lactate by Reversed-Phase Liquid Chromatography Tandem Mass Spectrometry
Background. Plasma and urinary levels of D-lactate have been linked to the presence of diabetes. Previously developed techniques have shown several limitations to further evaluate D-lactate as a biomarker for this condition. Methods. D- and L-lactate were quantified using ultraperformance liquid chr...
Autores principales: | Scheijen, Jean L. J. M., Hanssen, Nordin M. J., van de Waarenburg, Marjo P. H., Jonkers, Daisy M. A. E., Stehouwer, Coen D. A., Schalkwijk, Casper G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310144/ https://www.ncbi.nlm.nih.gov/pubmed/22474418 http://dx.doi.org/10.1155/2012/234812 |
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