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ArraySearch: A Web-Based Genomic Search Engine
Recent advances in microarray technologies have resulted in a flood of genomics data. This large body of accumulated data could be used as a knowledge base to help researchers interpret new experimental data. ArraySearch finds statistical correlations between newly observed gene expression profiles...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310226/ https://www.ncbi.nlm.nih.gov/pubmed/22474412 http://dx.doi.org/10.1155/2012/650842 |
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author | Wilson, Tyler J. Ge, Steven X. |
author_facet | Wilson, Tyler J. Ge, Steven X. |
author_sort | Wilson, Tyler J. |
collection | PubMed |
description | Recent advances in microarray technologies have resulted in a flood of genomics data. This large body of accumulated data could be used as a knowledge base to help researchers interpret new experimental data. ArraySearch finds statistical correlations between newly observed gene expression profiles and the huge source of well-characterized expression signatures deposited in the public domain. A search query of a list of genes will return experiments on which the genes are significantly up- or downregulated collectively. Searches can also be conducted using gene expression signatures from new experiments. This resource will empower biological researchers with a statistical method to explore expression data from their own research by comparing it with expression signatures from a large public archive. |
format | Online Article Text |
id | pubmed-3310226 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33102262012-04-03 ArraySearch: A Web-Based Genomic Search Engine Wilson, Tyler J. Ge, Steven X. Comp Funct Genomics Research Article Recent advances in microarray technologies have resulted in a flood of genomics data. This large body of accumulated data could be used as a knowledge base to help researchers interpret new experimental data. ArraySearch finds statistical correlations between newly observed gene expression profiles and the huge source of well-characterized expression signatures deposited in the public domain. A search query of a list of genes will return experiments on which the genes are significantly up- or downregulated collectively. Searches can also be conducted using gene expression signatures from new experiments. This resource will empower biological researchers with a statistical method to explore expression data from their own research by comparing it with expression signatures from a large public archive. Hindawi Publishing Corporation 2012 2012-03-04 /pmc/articles/PMC3310226/ /pubmed/22474412 http://dx.doi.org/10.1155/2012/650842 Text en Copyright © 2012 T. J. Wilson and S. X. Ge. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Wilson, Tyler J. Ge, Steven X. ArraySearch: A Web-Based Genomic Search Engine |
title | ArraySearch: A Web-Based Genomic Search Engine |
title_full | ArraySearch: A Web-Based Genomic Search Engine |
title_fullStr | ArraySearch: A Web-Based Genomic Search Engine |
title_full_unstemmed | ArraySearch: A Web-Based Genomic Search Engine |
title_short | ArraySearch: A Web-Based Genomic Search Engine |
title_sort | arraysearch: a web-based genomic search engine |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310226/ https://www.ncbi.nlm.nih.gov/pubmed/22474412 http://dx.doi.org/10.1155/2012/650842 |
work_keys_str_mv | AT wilsontylerj arraysearchawebbasedgenomicsearchengine AT gestevenx arraysearchawebbasedgenomicsearchengine |