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MicroRNA-34a Inhibits the Proliferation and Metastasis of Osteosarcoma Cells Both In Vitro and In Vivo

BACKGROUND: MicroRNAs (miRNAs) are a class of endogenously expressed, small noncoding RNAs, which suppress its target mRNAs at the post-transcriptional level. Studies have demonstrated that miR-34a, which is a direct target of the p53 tumor suppressor gene, functions as a tumor suppressor and is ass...

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Detalles Bibliográficos
Autores principales:	Yan, Kang, Gao, Jie, Yang, Tongtao, Ma, Qiong, Qiu, Xiuchun, Fan, Qingyu, Ma, Baoan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310405/ https://www.ncbi.nlm.nih.gov/pubmed/22457788 http://dx.doi.org/10.1371/journal.pone.0033778

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