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Multidrug-resistant Tuberculosis Detection, Latvia

To improve multidrug-resistant tuberculosis (MDR-TB) detection, we successfully introduced the rpoB gene mutation line probe assay into the national laboratory in Latvia, a country with epidemic MDR-TB. The assay detected rifampin resistance with 91% sensitivity and 96% specificity within 1 to 5 day...

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Autores principales: Skenders, Girts, Fry, Alicia M., Prokopovica, Inga, Greckoseja, Silvija, Broka, Lonija, Metchock, Beverly, Holtz, Timothy H., Wells, Charles D., Leimane, Vaira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310615/
https://www.ncbi.nlm.nih.gov/pubmed/16229783
http://dx.doi.org/10.3201/eid1109.041236
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author Skenders, Girts
Fry, Alicia M.
Prokopovica, Inga
Greckoseja, Silvija
Broka, Lonija
Metchock, Beverly
Holtz, Timothy H.
Wells, Charles D.
Leimane, Vaira
author_facet Skenders, Girts
Fry, Alicia M.
Prokopovica, Inga
Greckoseja, Silvija
Broka, Lonija
Metchock, Beverly
Holtz, Timothy H.
Wells, Charles D.
Leimane, Vaira
author_sort Skenders, Girts
collection PubMed
description To improve multidrug-resistant tuberculosis (MDR-TB) detection, we successfully introduced the rpoB gene mutation line probe assay into the national laboratory in Latvia, a country with epidemic MDR-TB. The assay detected rifampin resistance with 91% sensitivity and 96% specificity within 1 to 5 days (vs. 12–47 days for BACTEC).
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spelling pubmed-33106152012-04-06 Multidrug-resistant Tuberculosis Detection, Latvia Skenders, Girts Fry, Alicia M. Prokopovica, Inga Greckoseja, Silvija Broka, Lonija Metchock, Beverly Holtz, Timothy H. Wells, Charles D. Leimane, Vaira Emerg Infect Dis Dispatch To improve multidrug-resistant tuberculosis (MDR-TB) detection, we successfully introduced the rpoB gene mutation line probe assay into the national laboratory in Latvia, a country with epidemic MDR-TB. The assay detected rifampin resistance with 91% sensitivity and 96% specificity within 1 to 5 days (vs. 12–47 days for BACTEC). Centers for Disease Control and Prevention 2005-09 /pmc/articles/PMC3310615/ /pubmed/16229783 http://dx.doi.org/10.3201/eid1109.041236 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Skenders, Girts
Fry, Alicia M.
Prokopovica, Inga
Greckoseja, Silvija
Broka, Lonija
Metchock, Beverly
Holtz, Timothy H.
Wells, Charles D.
Leimane, Vaira
Multidrug-resistant Tuberculosis Detection, Latvia
title Multidrug-resistant Tuberculosis Detection, Latvia
title_full Multidrug-resistant Tuberculosis Detection, Latvia
title_fullStr Multidrug-resistant Tuberculosis Detection, Latvia
title_full_unstemmed Multidrug-resistant Tuberculosis Detection, Latvia
title_short Multidrug-resistant Tuberculosis Detection, Latvia
title_sort multidrug-resistant tuberculosis detection, latvia
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310615/
https://www.ncbi.nlm.nih.gov/pubmed/16229783
http://dx.doi.org/10.3201/eid1109.041236
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