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β-Lactam Resistance and Enterobacteriaceae, United States

Extended-spectrum cephalosporins (ESC) are an important drug class for treating severe Salmonella infections. We screened the human collection from the National Antimicrobial Resistance Monitoring System 2000 for ESC resistance mechanisms. Of non-Typhi Salmonella tested, 3.2% (44/1,378) contained bl...

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Detalles Bibliográficos
Autores principales: Whichard, Jean M., Joyce, Kevin, Fey, Paul D., Nelson, Jennifer M., Angulo, Frederick J., Barrett, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310626/
https://www.ncbi.nlm.nih.gov/pubmed/16229784
http://dx.doi.org/10.3201/eid1109.050182
Descripción
Sumario:Extended-spectrum cephalosporins (ESC) are an important drug class for treating severe Salmonella infections. We screened the human collection from the National Antimicrobial Resistance Monitoring System 2000 for ESC resistance mechanisms. Of non-Typhi Salmonella tested, 3.2% (44/1,378) contained bla(CMY) genes. Novel findings included bla(CMY)-positive Escherichia coli O157:H7 and a bla(SHV)-positive Salmonella isolate. CMY-positive isolates showed a ceftriaxone MIC >2 µg/mL.