Variant Creutzfeldt-Jakob Disease Death, United States

The only variant Creutzfeldt-Jakob disease (vCJD) patient identified in the United States died in 2004, and the diagnosis was confirmed by analysis of autopsy tissue. The patient likely acquired the disease while growing up in Great Britain before immigrating to the United States in 1992. Additional...

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Autores principales: Belay, Ermias D., Sejvar, James J., Shieh, Wun-Ju, Wiersma, Steven T., Zou, Wen-Quan, Gambetti, Pierluigi, Hunter, Stephen, Maddox, Ryan A., Crockett, Landis, Zaki, Sherif R., Schonberger, Lawrence B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310634/
https://www.ncbi.nlm.nih.gov/pubmed/16229761
http://dx.doi.org/10.3201/eid1109.050371
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author Belay, Ermias D.
Sejvar, James J.
Shieh, Wun-Ju
Wiersma, Steven T.
Zou, Wen-Quan
Gambetti, Pierluigi
Hunter, Stephen
Maddox, Ryan A.
Crockett, Landis
Zaki, Sherif R.
Schonberger, Lawrence B.
author_facet Belay, Ermias D.
Sejvar, James J.
Shieh, Wun-Ju
Wiersma, Steven T.
Zou, Wen-Quan
Gambetti, Pierluigi
Hunter, Stephen
Maddox, Ryan A.
Crockett, Landis
Zaki, Sherif R.
Schonberger, Lawrence B.
author_sort Belay, Ermias D.
collection PubMed
description The only variant Creutzfeldt-Jakob disease (vCJD) patient identified in the United States died in 2004, and the diagnosis was confirmed by analysis of autopsy tissue. The patient likely acquired the disease while growing up in Great Britain before immigrating to the United States in 1992. Additional vCJD patients continue to be identified outside the United Kingdom, including 2 more patients in Ireland, and 1 patient each in Japan, Portugal, Saudi Arabia, Spain, and the Netherlands. The reports of bloodborne transmission of vCJD in 2 patients, 1 of whom was heterozygous for methionine and valine at polymorphic codon 129, add to the uncertainty about the future of the vCJD outbreak.
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spelling pubmed-33106342012-04-06 Variant Creutzfeldt-Jakob Disease Death, United States Belay, Ermias D. Sejvar, James J. Shieh, Wun-Ju Wiersma, Steven T. Zou, Wen-Quan Gambetti, Pierluigi Hunter, Stephen Maddox, Ryan A. Crockett, Landis Zaki, Sherif R. Schonberger, Lawrence B. Emerg Infect Dis Research The only variant Creutzfeldt-Jakob disease (vCJD) patient identified in the United States died in 2004, and the diagnosis was confirmed by analysis of autopsy tissue. The patient likely acquired the disease while growing up in Great Britain before immigrating to the United States in 1992. Additional vCJD patients continue to be identified outside the United Kingdom, including 2 more patients in Ireland, and 1 patient each in Japan, Portugal, Saudi Arabia, Spain, and the Netherlands. The reports of bloodborne transmission of vCJD in 2 patients, 1 of whom was heterozygous for methionine and valine at polymorphic codon 129, add to the uncertainty about the future of the vCJD outbreak. Centers for Disease Control and Prevention 2005-09 /pmc/articles/PMC3310634/ /pubmed/16229761 http://dx.doi.org/10.3201/eid1109.050371 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Belay, Ermias D.
Sejvar, James J.
Shieh, Wun-Ju
Wiersma, Steven T.
Zou, Wen-Quan
Gambetti, Pierluigi
Hunter, Stephen
Maddox, Ryan A.
Crockett, Landis
Zaki, Sherif R.
Schonberger, Lawrence B.
Variant Creutzfeldt-Jakob Disease Death, United States
title Variant Creutzfeldt-Jakob Disease Death, United States
title_full Variant Creutzfeldt-Jakob Disease Death, United States
title_fullStr Variant Creutzfeldt-Jakob Disease Death, United States
title_full_unstemmed Variant Creutzfeldt-Jakob Disease Death, United States
title_short Variant Creutzfeldt-Jakob Disease Death, United States
title_sort variant creutzfeldt-jakob disease death, united states
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310634/
https://www.ncbi.nlm.nih.gov/pubmed/16229761
http://dx.doi.org/10.3201/eid1109.050371
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