Cargando…
Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance
Activation of oncogenes is generally associated with the induction of DNA damage response (DDR) signaling, which acts as a barrier to tumor progression. In this review we will present an overview of the DDR associated with oncogenic activation of Myc, with special focus on two opposite and paradoxic...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310713/ https://www.ncbi.nlm.nih.gov/pubmed/22373487 http://dx.doi.org/10.1186/1747-1028-7-6 |