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Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice

BACKGROUND: Recent in vivo and in vitro studies in non-neuronal and neuronal tissues have shown that different pathways of macrophage activation result in cells with different properties. Interleukin (IL)-6 triggers the classically activated inflammatory macrophages (M1 phenotype), whereas the alter...

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Detalles Bibliográficos
Autores principales:	Guerrero, Alexander Rodriguez, Uchida, Kenzo, Nakajima, Hideaki, Watanabe, Shuji, Nakamura, Masaya, Johnson, William EB, Baba, Hisatoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310810/ https://www.ncbi.nlm.nih.gov/pubmed/22369693 http://dx.doi.org/10.1186/1742-2094-9-40

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