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Benzyl Isothiocyanate Causes FoxO1-Mediated Autophagic Death in Human Breast Cancer Cells

Benzyl isothiocyanate (BITC), a constituent of edible cruciferous vegetables, inhibits growth of breast cancer cells but the mechanisms underlying growth inhibitory effect of BITC are not fully understood. Here, we demonstrate that BITC treatment causes FoxO1-mediated autophagic death in cultured hu...

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Detalles Bibliográficos
Autores principales: Xiao, Dong, Bommareddy, Ajay, Kim, Su-Hyeong, Sehrawat, Anuradha, Hahm, Eun-Ryeong, Singh, Shivendra V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310839/
https://www.ncbi.nlm.nih.gov/pubmed/22457718
http://dx.doi.org/10.1371/journal.pone.0032597

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