RUNX3 Mediates Suppression of Tumor Growth and Metastasis of Human CCRCC by Regulating Cyclin Related Proteins and TIMP-1

Here we presented that the expression of RUNX3 was significantly decreased in 75 cases of clear cell renal cell carcinoma (CCRCC) tissues (p<0.05). Enforced RUNX3 expression mediated 786-O cells to exhibit inhibition of growth, G1 cell-cycle arrest and metastasis in vitro, and to lost tumorigenic...

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Detalles Bibliográficos
Autores principales: He, Lijie, Zhao, Xiaodi, Wang, Hanmin, Zhang, Peng, Guo, Changcun, Huang, Chen, Liu, Xiaowei, Yao, Fangfang, Chen, Yu, Lou, Weijuan, Sun, Shiren, Fan, Daiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310845/
https://www.ncbi.nlm.nih.gov/pubmed/22457727
http://dx.doi.org/10.1371/journal.pone.0032961

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