Rationalization and Design of the Complementarity Determining Region Sequences in an Antibody-Antigen Recognition Interface

Protein-protein interactions are critical determinants in biological systems. Engineered proteins binding to specific areas on protein surfaces could lead to therapeutics or diagnostics for treating diseases in humans. But designing epitope-specific protein-protein interactions with computational at...

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Detalles Bibliográficos
Autores principales: Yu, Chung-Ming, Peng, Hung-Pin, Chen, Ing-Chien, Lee, Yu-Ching, Chen, Jun-Bo, Tsai, Keng-Chang, Chen, Ching-Tai, Chang, Jeng-Yih, Yang, Ei-Wen, Hsu, Po-Chiang, Jian, Jhih-Wei, Hsu, Hung-Ju, Chang, Hung-Ju, Hsu, Wen-Lian, Huang, Kai-Fa, Ma, Alex Che, Yang, An-Suei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310866/
https://www.ncbi.nlm.nih.gov/pubmed/22457753
http://dx.doi.org/10.1371/journal.pone.0033340

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