Nanostructured Oxygen Sensor - Using Micelles to Incorporate a Hydrophobic Platinum Porphyrin

Hydrophobic platinum(II)-5,10,15,20-tetrakis-(2,3,4,5,6-pentafluorophenyl)-porphyrin (PtTFPP) was physically incorporated into micelles formed from poly(ε-caprolactone)-block-poly(ethylene glycol) to enable the application of PtTFPP in aqueous solution. Micelles were characterized using dynamic ligh...

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Detalles Bibliográficos
Autores principales: Su, Fengyu, Alam, Ruhaniyah, Mei, Qian, Tian, Yanqing, Youngbull, Cody, Johnson, Roger H., Meldrum, Deirdre R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310867/
https://www.ncbi.nlm.nih.gov/pubmed/22457758
http://dx.doi.org/10.1371/journal.pone.0033390
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author Su, Fengyu
Alam, Ruhaniyah
Mei, Qian
Tian, Yanqing
Youngbull, Cody
Johnson, Roger H.
Meldrum, Deirdre R.
author_facet Su, Fengyu
Alam, Ruhaniyah
Mei, Qian
Tian, Yanqing
Youngbull, Cody
Johnson, Roger H.
Meldrum, Deirdre R.
author_sort Su, Fengyu
collection PubMed
description Hydrophobic platinum(II)-5,10,15,20-tetrakis-(2,3,4,5,6-pentafluorophenyl)-porphyrin (PtTFPP) was physically incorporated into micelles formed from poly(ε-caprolactone)-block-poly(ethylene glycol) to enable the application of PtTFPP in aqueous solution. Micelles were characterized using dynamic light scattering (DLS) and atomic force microscopy (AFM) to show an average diameter of about 140 nm. PtTFPP showed higher quantum efficiency in micellar solution than in tetrahydrofuran (THF) and dichloromethane (CH(2)Cl(2)). PtTFPP in micelles also exhibited higher photostability than that of PtTFPP suspended in water. PtTFPP in micelles exhibited good oxygen sensitivity and response time. This study provided an efficient approach to enable the application of hydrophobic oxygen sensors in a biological environment.
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spelling pubmed-33108672012-03-28 Nanostructured Oxygen Sensor - Using Micelles to Incorporate a Hydrophobic Platinum Porphyrin Su, Fengyu Alam, Ruhaniyah Mei, Qian Tian, Yanqing Youngbull, Cody Johnson, Roger H. Meldrum, Deirdre R. PLoS One Research Article Hydrophobic platinum(II)-5,10,15,20-tetrakis-(2,3,4,5,6-pentafluorophenyl)-porphyrin (PtTFPP) was physically incorporated into micelles formed from poly(ε-caprolactone)-block-poly(ethylene glycol) to enable the application of PtTFPP in aqueous solution. Micelles were characterized using dynamic light scattering (DLS) and atomic force microscopy (AFM) to show an average diameter of about 140 nm. PtTFPP showed higher quantum efficiency in micellar solution than in tetrahydrofuran (THF) and dichloromethane (CH(2)Cl(2)). PtTFPP in micelles also exhibited higher photostability than that of PtTFPP suspended in water. PtTFPP in micelles exhibited good oxygen sensitivity and response time. This study provided an efficient approach to enable the application of hydrophobic oxygen sensors in a biological environment. Public Library of Science 2012-03-22 /pmc/articles/PMC3310867/ /pubmed/22457758 http://dx.doi.org/10.1371/journal.pone.0033390 Text en Su et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Su, Fengyu
Alam, Ruhaniyah
Mei, Qian
Tian, Yanqing
Youngbull, Cody
Johnson, Roger H.
Meldrum, Deirdre R.
Nanostructured Oxygen Sensor - Using Micelles to Incorporate a Hydrophobic Platinum Porphyrin
title Nanostructured Oxygen Sensor - Using Micelles to Incorporate a Hydrophobic Platinum Porphyrin
title_full Nanostructured Oxygen Sensor - Using Micelles to Incorporate a Hydrophobic Platinum Porphyrin
title_fullStr Nanostructured Oxygen Sensor - Using Micelles to Incorporate a Hydrophobic Platinum Porphyrin
title_full_unstemmed Nanostructured Oxygen Sensor - Using Micelles to Incorporate a Hydrophobic Platinum Porphyrin
title_short Nanostructured Oxygen Sensor - Using Micelles to Incorporate a Hydrophobic Platinum Porphyrin
title_sort nanostructured oxygen sensor - using micelles to incorporate a hydrophobic platinum porphyrin
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310867/
https://www.ncbi.nlm.nih.gov/pubmed/22457758
http://dx.doi.org/10.1371/journal.pone.0033390
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