MUC1 Contributes to BPDE-Induced Human Bronchial Epithelial Cell Transformation through Facilitating EGFR Activation

Although it is well known that epidermal growth factor receptor (EGFR) is involved in lung cancer progression, whether EGFR contributes to lung epithelial cell transformation is less clear. Mucin 1 (MUC1 in human and Muc1 in animals), a glycoprotein component of airway mucus, is overexpressed in lun...

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Detalles Bibliográficos
Autores principales: Xu, Xiuling, Bai, Lang, Chen, Wenshu, Padilla, Mabel T., Liu, Yushi, Kim, Kwang Chul, Belinsky, Steven A., Lin, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310874/
https://www.ncbi.nlm.nih.gov/pubmed/22457794
http://dx.doi.org/10.1371/journal.pone.0033846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310874/
https://www.ncbi.nlm.nih.gov/pubmed/22457794
http://dx.doi.org/10.1371/journal.pone.0033846

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