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Optical and Digital Microscopic Imaging Techniques and Applications in Pathology

The conventional optical microscope has been the primary tool in assisting pathological examinations. The modern digital pathology combines the power of microscopy, electronic detection, and computerized analysis. It enables cellular-, molecular-, and genetic-imaging at high efficiency and accuracy...

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Detalles Bibliográficos
Autores principales: Chen, Xiaodong, Zheng, Bin, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310926/
https://www.ncbi.nlm.nih.gov/pubmed/21483100
http://dx.doi.org/10.3233/ACP-2011-0006
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author Chen, Xiaodong
Zheng, Bin
Liu, Hong
author_facet Chen, Xiaodong
Zheng, Bin
Liu, Hong
author_sort Chen, Xiaodong
collection PubMed
description The conventional optical microscope has been the primary tool in assisting pathological examinations. The modern digital pathology combines the power of microscopy, electronic detection, and computerized analysis. It enables cellular-, molecular-, and genetic-imaging at high efficiency and accuracy to facilitate clinical screening and diagnosis. This paper first reviews the fundamental concepts of microscopic imaging and introduces the technical features and associated clinical applications of optical microscopes, electron microscopes, scanning tunnel microscopes, and fluorescence microscopes. The interface of microscopy with digital image acquisition methods is discussed. The recent developments and future perspectives of contemporary microscopic imaging techniques such as three-dimensional and in vivo imaging are analyzed for their clinical potentials.
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spelling pubmed-33109262012-03-23 Optical and Digital Microscopic Imaging Techniques and Applications in Pathology Chen, Xiaodong Zheng, Bin Liu, Hong Anal Cell Pathol (Amst) Other The conventional optical microscope has been the primary tool in assisting pathological examinations. The modern digital pathology combines the power of microscopy, electronic detection, and computerized analysis. It enables cellular-, molecular-, and genetic-imaging at high efficiency and accuracy to facilitate clinical screening and diagnosis. This paper first reviews the fundamental concepts of microscopic imaging and introduces the technical features and associated clinical applications of optical microscopes, electron microscopes, scanning tunnel microscopes, and fluorescence microscopes. The interface of microscopy with digital image acquisition methods is discussed. The recent developments and future perspectives of contemporary microscopic imaging techniques such as three-dimensional and in vivo imaging are analyzed for their clinical potentials. IOS Press 2011 2011-03-25 /pmc/articles/PMC3310926/ /pubmed/21483100 http://dx.doi.org/10.3233/ACP-2011-0006 Text en Copyright © 2011 Hindawi Publishing Corporation and the authors.
spellingShingle Other
Chen, Xiaodong
Zheng, Bin
Liu, Hong
Optical and Digital Microscopic Imaging Techniques and Applications in Pathology
title Optical and Digital Microscopic Imaging Techniques and Applications in Pathology
title_full Optical and Digital Microscopic Imaging Techniques and Applications in Pathology
title_fullStr Optical and Digital Microscopic Imaging Techniques and Applications in Pathology
title_full_unstemmed Optical and Digital Microscopic Imaging Techniques and Applications in Pathology
title_short Optical and Digital Microscopic Imaging Techniques and Applications in Pathology
title_sort optical and digital microscopic imaging techniques and applications in pathology
topic Other
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310926/
https://www.ncbi.nlm.nih.gov/pubmed/21483100
http://dx.doi.org/10.3233/ACP-2011-0006
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