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A novel k-mer mixture logistic regression for methylation susceptibility modeling of CpG dinucleotides in human gene promoters

BACKGROUND: DNA methylation is essential for normal development and differentiation and plays a crucial role in the development of nearly all types of cancer. Aberrant DNA methylation patterns, including genome-wide hypomethylation and region-specific hypermethylation, are frequently observed and co...

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Detalles Bibliográficos
Autores principales:	Yang, Youngik, Nephew, Kenneth, Kim, Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311103/ https://www.ncbi.nlm.nih.gov/pubmed/22536899 http://dx.doi.org/10.1186/1471-2105-13-S3-S15

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