Molecular Epidemiology of Rift Valley Fever Virus

Phylogenetic relationships were examined for 198 Rift Valley fever virus isolates and 5 derived strains obtained from various sources in Saudi Arabia and 16 countries in Africa during a 67-year period (1944–2010). A maximum-likelihood tree prepared with sequence data for a 490-nt section of the Gn g...

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Autores principales: Grobbelaar, Antoinette A., Weyer, Jacqueline, Leman, Patricia A., Kemp, Alan, Paweska, Janusz T., Swanepoel, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311189/
https://www.ncbi.nlm.nih.gov/pubmed/22172568
http://dx.doi.org/10.3201/eid1712.111035
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author Grobbelaar, Antoinette A.
Weyer, Jacqueline
Leman, Patricia A.
Kemp, Alan
Paweska, Janusz T.
Swanepoel, Robert
author_facet Grobbelaar, Antoinette A.
Weyer, Jacqueline
Leman, Patricia A.
Kemp, Alan
Paweska, Janusz T.
Swanepoel, Robert
author_sort Grobbelaar, Antoinette A.
collection PubMed
description Phylogenetic relationships were examined for 198 Rift Valley fever virus isolates and 5 derived strains obtained from various sources in Saudi Arabia and 16 countries in Africa during a 67-year period (1944–2010). A maximum-likelihood tree prepared with sequence data for a 490-nt section of the Gn glycoprotein gene showed that 95 unique sequences sorted into 15 lineages. A 2010 isolate from a patient in South Africa potentially exposed to co-infection with live animal vaccine and wild virus was a reassortant. The potential influence of large-scale use of live animal vaccine on evolution of Rift Valley fever virus is discussed.
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spelling pubmed-33111892012-04-06 Molecular Epidemiology of Rift Valley Fever Virus Grobbelaar, Antoinette A. Weyer, Jacqueline Leman, Patricia A. Kemp, Alan Paweska, Janusz T. Swanepoel, Robert Emerg Infect Dis Research Phylogenetic relationships were examined for 198 Rift Valley fever virus isolates and 5 derived strains obtained from various sources in Saudi Arabia and 16 countries in Africa during a 67-year period (1944–2010). A maximum-likelihood tree prepared with sequence data for a 490-nt section of the Gn glycoprotein gene showed that 95 unique sequences sorted into 15 lineages. A 2010 isolate from a patient in South Africa potentially exposed to co-infection with live animal vaccine and wild virus was a reassortant. The potential influence of large-scale use of live animal vaccine on evolution of Rift Valley fever virus is discussed. Centers for Disease Control and Prevention 2011-12 /pmc/articles/PMC3311189/ /pubmed/22172568 http://dx.doi.org/10.3201/eid1712.111035 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Grobbelaar, Antoinette A.
Weyer, Jacqueline
Leman, Patricia A.
Kemp, Alan
Paweska, Janusz T.
Swanepoel, Robert
Molecular Epidemiology of Rift Valley Fever Virus
title Molecular Epidemiology of Rift Valley Fever Virus
title_full Molecular Epidemiology of Rift Valley Fever Virus
title_fullStr Molecular Epidemiology of Rift Valley Fever Virus
title_full_unstemmed Molecular Epidemiology of Rift Valley Fever Virus
title_short Molecular Epidemiology of Rift Valley Fever Virus
title_sort molecular epidemiology of rift valley fever virus
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311189/
https://www.ncbi.nlm.nih.gov/pubmed/22172568
http://dx.doi.org/10.3201/eid1712.111035
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