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EP(2) and EP(4) receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals

Intestinal resident macrophages play an important role in gastrointestinal dysmotility by producing prostaglandins (PGs) and nitric oxide (NO) in inflammatory conditions. The causal correlation between PGs and NO in gastrointestinal inflammation has not been elucidated. In this study, we examined th...

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Detalles Bibliográficos
Autores principales:	Tajima, Tsuyoshi, Murata, Takahisa, Aritake, Kosuke, Urade, Yoshihiro, Michishita, Masaki, Matsuoka, Toshiyuki, Narumiya, Shuh, Ozaki, Hiroshi, Hori, Masatoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2012
Materias:	Inflammation/Immunity/Mediators
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311437/ https://www.ncbi.nlm.nih.gov/pubmed/22159280 http://dx.doi.org/10.1152/ajpgi.00264.2011

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