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Metabolite proving fungal cleavage of the aromatic core part of a fluoroquinolone antibiotic

Liquid cultures of the basidiomycetous fungus Gloeophyllum striatum were employed to study the biodegradation of pradofloxacin, a new veterinary fluoroquinolone antibiotic carrying a CN group at position C-8. After 16 days of incubation, metabolites were purified by micro-preparative high-performanc...

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Detalles Bibliográficos
Autores principales: Wetzstein, Heinz-Georg, Schneider, Josef, Karl, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311597/
https://www.ncbi.nlm.nih.gov/pubmed/22214407
http://dx.doi.org/10.1186/2191-0855-2-3

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