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Puerarin Induces Mitochondria-Dependent Apoptosis in Hypoxic Human Pulmonary Arterial Smooth Muscle Cells

BACKGROUND: Pulmonary vascular medial hypertrophy in hypoxic pulmonary arterial hypertension (PAH) is caused in part by decreased apoptosis in pulmonary artery smooth muscle cells (PASMCs). Puerarin, an isoflavone purified from the Chinese medicinal herb kudzu, ameliorates chronic hypoxic PAH in ani...

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Detalles Bibliográficos
Autores principales:	Chen, Chan, Chen, Chun, Wang, Zhiyi, Wang, Liangxing, Yang, Lehe, Ding, Minjiao, Ding, Cheng, Sun, Yu, Lin, Quan, Huang, Xiaoying, Du, Xiaohong, Zhao, Xiaowei, Wang, Chuangyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311615/ https://www.ncbi.nlm.nih.gov/pubmed/22457823 http://dx.doi.org/10.1371/journal.pone.0034181

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