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Generation of a Novel Nucleic Acid-Based Reporter System To Detect Phenotypic Susceptibility to Antibiotics in Mycobacterium tuberculosis

We designed, constructed, and evaluated a prototype novel reporter system comprised of two functional cassettes: (i) the SP6 RNA polymerase gene under transcriptional control of a promoter active in mycobacteria and (ii) the consensus SP6 polymerase promoter that directs expression of an otherwise u...

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Detalles Bibliográficos
Autores principales:	Mulvey, Matthew C., Sacksteder, Katherine A., Einck, Leo, Nacy, Carol A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312217/ https://www.ncbi.nlm.nih.gov/pubmed/22415006 http://dx.doi.org/10.1128/mBio.00312-11

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