Myocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle

Sepsis has high incidence and mortality rates around the world. The role of cardiac depression in myocardial dysfunction during sepsis remains to be elucidated. This review attempts to summarize our understanding of the anatomical, histopathological, and pathophysiological mechanisms behind cardiac...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandes Jr., Constantino Jose, de Assuncao, Murillo Santucci Cesar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312225/
https://www.ncbi.nlm.nih.gov/pubmed/22482045
http://dx.doi.org/10.1155/2012/896430
_version_ 1782227827153698816
author Fernandes Jr., Constantino Jose
de Assuncao, Murillo Santucci Cesar
author_facet Fernandes Jr., Constantino Jose
de Assuncao, Murillo Santucci Cesar
author_sort Fernandes Jr., Constantino Jose
collection PubMed
description Sepsis has high incidence and mortality rates around the world. The role of cardiac depression in myocardial dysfunction during sepsis remains to be elucidated. This review attempts to summarize our understanding of the anatomical, histopathological, and pathophysiological mechanisms behind cardiac dysfunction. Biomarkers to detect cardiac depression have been used to recognize developing problems, but the actual impact of these tools remains unclear.
format Online
Article
Text
id pubmed-3312225
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-33122252012-04-05 Myocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle Fernandes Jr., Constantino Jose de Assuncao, Murillo Santucci Cesar Crit Care Res Pract Review Article Sepsis has high incidence and mortality rates around the world. The role of cardiac depression in myocardial dysfunction during sepsis remains to be elucidated. This review attempts to summarize our understanding of the anatomical, histopathological, and pathophysiological mechanisms behind cardiac dysfunction. Biomarkers to detect cardiac depression have been used to recognize developing problems, but the actual impact of these tools remains unclear. Hindawi Publishing Corporation 2012 2012-03-13 /pmc/articles/PMC3312225/ /pubmed/22482045 http://dx.doi.org/10.1155/2012/896430 Text en Copyright © 2012 C. J. Fernandes Jr. and M. S. C. de Assuncao. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Fernandes Jr., Constantino Jose
de Assuncao, Murillo Santucci Cesar
Myocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle
title Myocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle
title_full Myocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle
title_fullStr Myocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle
title_full_unstemmed Myocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle
title_short Myocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle
title_sort myocardial dysfunction in sepsis: a large, unsolved puzzle
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312225/
https://www.ncbi.nlm.nih.gov/pubmed/22482045
http://dx.doi.org/10.1155/2012/896430
work_keys_str_mv AT fernandesjrconstantinojose myocardialdysfunctioninsepsisalargeunsolvedpuzzle
AT deassuncaomurillosantuccicesar myocardialdysfunctioninsepsisalargeunsolvedpuzzle

Ejemplares similares