Cargando…
Exploiting Surface Plasmon Resonance (SPR) Technology for the Identification of Fibroblast Growth Factor-2 (FGF2) Antagonists Endowed with Antiangiogenic Activity
Angiogenesis, the process of new blood vessel formation, is implicated in various physiological/pathological conditions, including embryonic development, inflammation and tumor growth. Fibroblast growth factor-2 (FGF2) is a heparin-binding angiogenic growth factor involved in various physiopathologi...
Autores principales: | Rusnati, Marco, Bugatti, Antonella, Mitola, Stefania, Leali, Daria, Bergese, Paolo, Depero, Laura E., Presta, Marco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312455/ https://www.ncbi.nlm.nih.gov/pubmed/22454596 http://dx.doi.org/10.3390/s90806471 |
Ejemplares similares
-
Thrombospondin-1 as a Paradigm for the Development of Antiangiogenic Agents Endowed with Multiple Mechanisms of Action
por: Rusnati, Marco, et al.
Publicado: (2010) -
Direct and Allosteric Inhibition of the FGF2/HSPGs/FGFR1 Ternary Complex Formation by an Antiangiogenic, Thrombospondin-1-Mimic Small Molecule
por: Pagano, Katiuscia, et al.
Publicado: (2012) -
Fibroblast growth factor 2-antagonist activity of a long-pentraxin 3-derived anti-angiogenic pentapeptide
por: Leali, Daria, et al.
Publicado: (2010) -
Integrating computational and chemical biology tools in the discovery of antiangiogenic small molecule ligands of FGF2 derived from endogenous inhibitors
por: Foglieni, Chiara, et al.
Publicado: (2016) -
Targeting tumor angiogenesis with TSP-1-based compounds: rational design of antiangiogenic mimetics of endogenous inhibitors
por: Taraboletti, Giulia, et al.
Publicado: (2010)