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Tumor necrosis factor-α-mediated threonine 435 phosphorylation of p65 nuclear factor-κB subunit in endothelial cells induces vasogenic edema and neutrophil infiltration in the rat piriform cortex following status epilepticus

BACKGROUND: Status epilepticus (SE) induces severe vasogenic edema in the piriform cortex (PC) accompanied by neuronal and astroglial damages. To elucidate the mechanism of SE-induced vasogenic edema, we investigated the roles of tumor necrosis factor (TNF)-α in blood-brain barrier (BBB) disruption...

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Detalles Bibliográficos
Autores principales:	Kim, Ji-Eun, Ryu, Hea Jin, Choi, Soo Young, Kang, Tae-Cheon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312845/ https://www.ncbi.nlm.nih.gov/pubmed/22240205 http://dx.doi.org/10.1186/1742-2094-9-6

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