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Age Affects Quantity but Not Quality of Antibody Responses after Vaccination with an Inactivated Flavivirus Vaccine against Tick-Borne Encephalitis

The impairment of immune functions in the elderly (immunosenescence) results in post-vaccination antibody titers that are significantly lower than in young individuals. It is, however, a controversial question whether also the quality of antibodies declines with age. In this study, we have therefore...

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Detalles Bibliográficos
Autores principales: Stiasny, Karin, Aberle, Judith H., Keller, Michael, Grubeck-Loebenstein, Beatrix, Heinz, Franz X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312914/
https://www.ncbi.nlm.nih.gov/pubmed/22461903
http://dx.doi.org/10.1371/journal.pone.0034145