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Activation of ERAD Pathway by Human Hepatitis B Virus Modulates Viral and Subviral Particle Production
Hepatitis B virus (HBV) belongs to the Hepadnaviridae family of enveloped DNA viruses. It was previously shown that HBV can induce endoplasmic reticulum (ER) stress and activate the IRE1-XBP1 pathway of the unfolded protein response (UPR), through the expression of the viral regulatory protein X (HB...
Autores principales: | Lazar, Catalin, Macovei, Alina, Petrescu, Stefana, Branza-Nichita, Norica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312915/ https://www.ncbi.nlm.nih.gov/pubmed/22461906 http://dx.doi.org/10.1371/journal.pone.0034169 |
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