Cargando…

Protein Kinase D Regulates Cell Death Pathways in Experimental Pancreatitis

Inflammation and acinar cell necrosis are two major pathological responses of acute pancreatitis, a serious disorder with no current therapies directed to its molecular pathogenesis. Serine/threonine protein kinase D family, which includes PKD/PKD1, PKD2, and PKD3, has been increasingly implicated i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Jingzhen, Liu, Yannan, Tan, Tanya, Guha, Sushovan, Gukovsky, Ilya, Gukovskaya, Anna, Pandol, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313474/ https://www.ncbi.nlm.nih.gov/pubmed/22470346 http://dx.doi.org/10.3389/fphys.2012.00060

Ejemplares similares

Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis
por: Yuan, Jingzhen, et al.
Publicado: (2017)

Inhibitors of Bcl-2 protein family deplete ER Ca(2+) stores in pancreatic acinar cells
por: Gerasimenko, Julia, et al.
Publicado: (2010)

Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental Pancreatitis
por: Mareninova, Olga A., et al.
Publicado: (2021)

Proteomic Identification of Novel Plasma Biomarkers and Pathobiologic Pathways in Alcoholic Acute Pancreatitis
por: Waldron, Richard T., et al.
Publicado: (2018)

What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?
por: Pandol, Stephen J., et al.
Publicado: (2015)

Protective effects of urocortin 2 against caerulein-induced acute pancreatitis
por: Yuan, Jingzhen, et al.
Publicado: (2019)

The Potential for Circulating Tumor Cells in Pancreatic Cancer Management
por: Pimienta, Michael, et al.
Publicado: (2017)

Environmental and Genetic Stressors and the Unfolded Protein Response in Exocrine Pancreatic Function – A Hypothesis
por: Pandol, Stephen J., et al.
Publicado: (2011)

Diabetes, pancreatic cancer, and metformin therapy
por: Gong, Jun, et al.
Publicado: (2014)

Pancreatic cancer cachexia: a review of mechanisms and therapeutics
por: Tan, Carlyn R., et al.
Publicado: (2014)

MSP-RON Signaling Is Activated in the Transition From Pancreatic Intraepithelial Neoplasia (PanIN) to Pancreatic Ductal Adenocarcinoma (PDAC)
por: Li, Ce, et al.
Publicado: (2019)

Incidence of New Onset Diabetes Mellitus Secondary to Acute Pancreatitis: A Systematic Review and Meta-Analysis
por: Zhi, Mengmeng, et al.
Publicado: (2019)

Corrigendum: The Future of Gastrointestinal Physiology: 2020 and Beyond
por: Pandol, Stephen
Publicado: (2021)

The Future of Gastrointestinal Physiology: 2020 and Beyond
por: Pandol, Stephen
Publicado: (2021)

Yes-Associated Protein 1 Plays Major Roles in Pancreatic Stellate Cell Activation and Fibroinflammatory Responses
por: Hu, Cheng, et al.
Publicado: (2019)

Integrating the Gastrointestinal Sciences
por: Pandol, Stephen J.
Publicado: (2010)

Phosphoinositide 3-Kinase Signaling Pathway in Pancreatic Ductal Adenocarcinoma Progression, Pathogenesis, and Therapeutics
por: Murthy, Divya, et al.
Publicado: (2018)

Uniting Epidemiology and Experimental Models: Pancreatic Steatosis and Pancreatic Cancer
por: Truong, Emily, et al.
Publicado: (2022)

Circulating Fatty Objects and Their Preferential Presence in Pancreatic Cancer Patient Blood Samples
por: Wang, Ruoxiang, et al.
Publicado: (2022)

Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice
por: Sendler, Matthias, et al.
Publicado: (2018)

Lysosome-Associated Membrane Proteins (LAMP) Maintain Pancreatic Acinar Cell Homeostasis: LAMP-2–Deficient Mice Develop Pancreatitis
por: Mareninova, Olga A., et al.
Publicado: (2015)

Multiparametric Mapping Magnetic Resonance Imaging of Pancreatic Disease
por: Wang, Lixia, et al.
Publicado: (2020)

Green Plant Pigment, Chlorophyllin, Ameliorates Non-alcoholic Fatty Liver Diseases (NAFLDs) Through Modulating Gut Microbiome in Mice
por: Yang, You, et al.
Publicado: (2021)

Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP
por: Mukherjee, Rajarshi, et al.
Publicado: (2016)

Src as the link between inflammation and cancer
por: Liu, Sandy T., et al.
Publicado: (2014)

Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin
por: Zhou, Guisheng, et al.
Publicado: (2014)

A potential signaling axis between RON kinase receptor and hypoxia‐inducible factor‐1 alpha in pancreatic cancer
por: Kato, Akihisa, et al.
Publicado: (2021)

EUS Morphology Is Reliable in Selecting Patients with Mucinous Pancreatic Cyst(s) Most Likely to Benefit from Surgical Resection
por: Javia, Siddharth, et al.
Publicado: (2017)

Glycogen Synthase Kinase 3β: A True Foe in Pancreatic Cancer
por: Elmadbouh, Omer H. M., et al.
Publicado: (2022)

Experimental Acute Pancreatitis Models: History, Current Status, and Role in Translational Research
por: Yang, Xinmin, et al.
Publicado: (2020)

Defects in Cytoskeletal Signaling Pathways, Arrhythmia, and Sudden Cardiac Death
por: Smith, Sakima, et al.
Publicado: (2012)

New Insights into Phospholipase D and Sphingosine Kinase Activation in Arabidopsis
por: Ng, Carl K.-Y., et al.
Publicado: (2012)

Uniting Epidemiology and Experimental Disease Models for Alcohol-Related Pancreatic Disease
por: Setiawan, Veronica Wendy, et al.
Publicado: (2017)

Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models
por: Su, Danmei, et al.
Publicado: (2016)

Mitochondrial Permeability Transition and Cell Death: The Role of Cyclophilin D
por: Javadov, Sabzali, et al.
Publicado: (2013)

Alternation of Gut Microbiota in Patients with Pulmonary Tuberculosis
por: Luo, Mei, et al.
Publicado: (2017)

Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D
por: Herwig, Melissa, et al.
Publicado: (2020)

Role of Phosphatidylinositol 3-Kinase (PI3K), Mitogen-Activated Protein Kinase (MAPK), and Protein Kinase C (PKC) in Calcium Signaling Pathways Linked to the α(1)-Adrenoceptor in Resistance Arteries
por: Gutiérrez, Alejandro, et al.
Publicado: (2019)

Role of the Extracellular Signal-Regulated Kinase 1/2 Signaling Pathway in Ischemia-Reperfusion Injury
por: Kong, Tingting, et al.
Publicado: (2019)

Tyrosine Kinase Inhibitors Reduce NMDA NR1 Subunit Expression, Nuclear Translocation, and Behavioral Pain Measures in Experimental Arthritis
por: Westlund, Karin N., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1gu765vgb86ffcoea9kkgqofhu