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Metformin (dimethyl-biguanide) induced DNA damage in mammalian cells

Metformin (dimethyl-biguanide) is an insulin-sensitizing agent that lowers fasting plasma-insulin concentration, wherefore it’s wide use for patients with a variety of insulin-resistant and prediabetic states, including impaired glucose tolerance. During pregnancy it is a further resource for reduci...

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Detalles Bibliográficos
Autores principales: Amador, Rubem R., Longo, João Paulo Figueiró, Lacava, Zulmira G., Dórea, José G., Almeida Santos, Maria de Fátima M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313505/
https://www.ncbi.nlm.nih.gov/pubmed/22481889

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