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Targeted Molecular Imaging of Angiogenesis in PET and SPECT: A Review

Over the past few decades, there have been significant advancements in the imaging techniques of positron emission tomography (PET) and single photon emission tomography (SPECT). These changes have allowed for the targeted imaging of cellular processes and the development of hybrid imaging systems (...

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Detalles Bibliográficos
Autores principales: Stacy, Mitchel R., Maxfield, Mark W., Sinusas, Albert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313541/
https://www.ncbi.nlm.nih.gov/pubmed/22461745
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author Stacy, Mitchel R.
Maxfield, Mark W.
Sinusas, Albert J.
author_facet Stacy, Mitchel R.
Maxfield, Mark W.
Sinusas, Albert J.
author_sort Stacy, Mitchel R.
collection PubMed
description Over the past few decades, there have been significant advancements in the imaging techniques of positron emission tomography (PET) and single photon emission tomography (SPECT). These changes have allowed for the targeted imaging of cellular processes and the development of hybrid imaging systems (e.g., SPECT/CT and PET/CT), which provide both functional and structural images of biological systems. One area that has garnered particular attention is angiogenesis as it relates to ischemic heart disease and limb ischemia. Though the aforementioned techniques have benefits and consequences, they enable scientists and clinicians to identify regions that are vulnerable to or have been exposed to ischemic injury via non-invasive means. This literature review highlights the advancements in molecular imaging techniques and specific probes as they pertain to the process of angiogenesis in cardiovascular disease.
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spelling pubmed-33135412012-03-29 Targeted Molecular Imaging of Angiogenesis in PET and SPECT: A Review Stacy, Mitchel R. Maxfield, Mark W. Sinusas, Albert J. Yale J Biol Med Focus: Translational Medicine Over the past few decades, there have been significant advancements in the imaging techniques of positron emission tomography (PET) and single photon emission tomography (SPECT). These changes have allowed for the targeted imaging of cellular processes and the development of hybrid imaging systems (e.g., SPECT/CT and PET/CT), which provide both functional and structural images of biological systems. One area that has garnered particular attention is angiogenesis as it relates to ischemic heart disease and limb ischemia. Though the aforementioned techniques have benefits and consequences, they enable scientists and clinicians to identify regions that are vulnerable to or have been exposed to ischemic injury via non-invasive means. This literature review highlights the advancements in molecular imaging techniques and specific probes as they pertain to the process of angiogenesis in cardiovascular disease. YJBM 2012-03-29 /pmc/articles/PMC3313541/ /pubmed/22461745 Text en Copyright ©2012, Yale Journal of Biology and Medicine https://creativecommons.org/licenses/by-nc/3.0/This is an open access article distributed under the terms of the Creative Commons CC BY-NC license, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use the material for commercial purposes.
spellingShingle Focus: Translational Medicine
Stacy, Mitchel R.
Maxfield, Mark W.
Sinusas, Albert J.
Targeted Molecular Imaging of Angiogenesis in PET and SPECT: A Review
title Targeted Molecular Imaging of Angiogenesis in PET and SPECT: A Review
title_full Targeted Molecular Imaging of Angiogenesis in PET and SPECT: A Review
title_fullStr Targeted Molecular Imaging of Angiogenesis in PET and SPECT: A Review
title_full_unstemmed Targeted Molecular Imaging of Angiogenesis in PET and SPECT: A Review
title_short Targeted Molecular Imaging of Angiogenesis in PET and SPECT: A Review
title_sort targeted molecular imaging of angiogenesis in pet and spect: a review
topic Focus: Translational Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313541/
https://www.ncbi.nlm.nih.gov/pubmed/22461745
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