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Inhibition of LPS-Induced Activation of Coagulation by p38 MAPK Inhibitor

During Gram-negative sepsis, lipopolysaccharide (LPS) activates toll-like receptor (TLR) 4 and induces complex responses of immune system and coagulation. However, the underlying LPS signalling mechanism on coagulation activation remains complex. To determine the role of the intracellular signalling...

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Detalles Bibliográficos
Autores principales: Koch, Lutz, Hofer, Stefan, Weigand, Markus A., Frommhold, David, Poeschl, Johannes, Ruef, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313583/
https://www.ncbi.nlm.nih.gov/pubmed/22461999
http://dx.doi.org/10.5402/2012/762614

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