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Inhibition of LPS-Induced Activation of Coagulation by p38 MAPK Inhibitor
During Gram-negative sepsis, lipopolysaccharide (LPS) activates toll-like receptor (TLR) 4 and induces complex responses of immune system and coagulation. However, the underlying LPS signalling mechanism on coagulation activation remains complex. To determine the role of the intracellular signalling...
Autores principales: | Koch, Lutz, Hofer, Stefan, Weigand, Markus A., Frommhold, David, Poeschl, Johannes, Ruef, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scholarly Research Network
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313583/ https://www.ncbi.nlm.nih.gov/pubmed/22461999 http://dx.doi.org/10.5402/2012/762614 |
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