Cargando…

CYP2J3 Gene Delivery Reduces Insulin Resistance via Upregulation of eNOS in Fructose-treated Rats

Accumulating evidence suggests that cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid into epoxyeicosatrienoic acids (EETs) which play important roles in various pathophysiological processes. Interestingly, CYP-derived eicosanoids are vasodilatory, at least in part through their ability...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Xizhen, Tu, Ling, Wang, Luyun, Fang, Xiaosai, Wang, Dao Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313895/ https://www.ncbi.nlm.nih.gov/pubmed/22189162 http://dx.doi.org/10.1186/1475-2840-10-114

Ejemplares similares

Correction: CYP2J3 gene delivery reduces insulin resistance via upregulation of eNOS in fructose-treated rats
por: Xu, Xizhen, et al.
Publicado: (2014)

Increased CYP2J3 Expression Reduces Insulin Resistance in Fructose-Treated Rats and db/db Mice
por: Xu, Xizhen, et al.
Publicado: (2010)

Upregulation of iNOS and phosphorylated eNOS in the implantation‐induced blastocysts of mice
por: Seki, Misato, et al.
Publicado: (2023)

Endothelium‐specific CYP2J2 overexpression attenuates age‐related insulin resistance
por: Yang, Yan, et al.
Publicado: (2018)

CYP2J2 and Its Metabolites EETs Attenuate Insulin Resistance via Regulating Macrophage Polarization in Adipose Tissue
por: Dai, Meiyan, et al.
Publicado: (2017)

Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009)

Deletion of GIT1 Impacts eNOS Activity To Aggravate sFlt-1–Induced Preeclampsia Phenotype in Mice
por: Zhang, Shenghong, et al.
Publicado: (2018)

SIRT1 protects against myocardial ischemia–reperfusion injury via activating eNOS in diabetic rats
por: Ding, Mingge, et al.
Publicado: (2015)

TNF-α induces vascular insulin resistance via positive modulation of PTEN and decreased Akt/eNOS/NO signaling in high fat diet-fed mice
por: da Costa, Rafael Menezes, et al.
Publicado: (2016)

mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncoupling
por: Wang, Yiying, et al.
Publicado: (2022)

High fructose induces dysfunctional vasodilatation via PP2A-mediated eNOS Ser1177 dephosphorylation
por: Jin, Jiaqi, et al.
Publicado: (2022)

p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-Uncoupling in Obesity
por: Yu, Yi, et al.
Publicado: (2014)

Association of genetic polymorphisms of eNOS with glaucoma
por: Liao, Qiong, et al.
Publicado: (2011)

Heterozygous eNOS Deficient Mice as a Model to Examine the Effects of eNOS Haploinsufficiency on the Cerebral Circulation
por: Didion, Sean P.
Publicado: (2017)

Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling
por: Mu, Haiman, et al.
Publicado: (2019)

N-acetylcysteine attenuates myocardial dysfunction and postischemic injury by restoring caveolin-3/eNOS signaling in diabetic rats
por: Su, Wating, et al.
Publicado: (2016)

Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice
por: Yu, Jia-Wen, et al.
Publicado: (2016)

Non-viral eNOS gene delivery and transfection with stents for the treatment of restenosis
por: Brito, Luis A, et al.
Publicado: (2010)

PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G(+) -Toxins
por: Chen, Feng, et al.
Publicado: (2014)

Berberine attenuates sepsis-induced cardiac dysfunction by upregulating the Akt/eNOS pathway in mice
por: Zhang, Hong, et al.
Publicado: (2022)

Metformin Prevents Endothelial Dysfunction in Endometriosis through Downregulation of ET-1 and Upregulation of eNOS
por: Martins, Ana Filipa, et al.
Publicado: (2022)

Naringenin upregulates GTPCH1/eNOS to ameliorate high glucose-induced retinal endothelial cell injury
por: Xue, Bing, et al.
Publicado: (2022)

Exercise training enhanced myocardial endothelial nitric oxide synthase (eNOS) function in diabetic Goto-Kakizaki (GK) rats
por: Grijalva, James, et al.
Publicado: (2008)

Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway
por: Dou, Jianxin, et al.
Publicado: (2014)

Endothelial NO Production Is Mandatory for Epigallocatechin-3-Gallate–induced Vasodilation: Results From eNOS Knockout (eNOS(−/−)) Mice
por: Lorenz, Mario, et al.
Publicado: (2015)

Multiple inducers of endothelial NOS (eNOS) dysfunction in sickle cell disease
por: Hebbel, Robert P., et al.
Publicado: (2021)

Tadalafil ameliorates bladder overactivity by restoring insulin-activated detrusor relaxation via the bladder mucosal IRS/PI3K/AKT/eNOS pathway in fructose-fed rats
por: Lee, Wei-Chia, et al.
Publicado: (2021)

Data on eNOS T786 and G894T polymorphisms and peripheral blood eNOS mRNA levels in Sickle Cell Disease
por: Armenis, Iakovos, et al.
Publicado: (2016)

Berberine Protects against Palmitate-Induced Endothelial Dysfunction: Involvements of Upregulation of AMPK and eNOS and Downregulation of NOX4
por: Zhang, Ming, et al.
Publicado: (2013)

Expression of eNOS in kidneys from hypertensive patients
por: Gu, Xin, et al.
Publicado: (2010)

Frequency of eNOS polymorphisms in the Colombian general population
por: Serrano, Norma C, et al.
Publicado: (2010)

Neurogranin regulates eNOS function and endothelial activation
por: Cheriyan, Vino T., et al.
Publicado: (2020)

Nitric oxide–dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition
por: Chen, Zhenlong, et al.
Publicado: (2012)

Paternal eNOS deficiency in mice affects glucose homeostasis and liver glycogen in male offspring without inheritance of eNOS deficiency itself
por: Hocher, Berthold, et al.
Publicado: (2022)

Recipient iNOS but Not eNOS Deficiency Reduces Luminal Narrowing in Tracheal Allografts
por: Minamoto, Kanji, et al.
Publicado: (2002)

Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS
por: Morsy, Mohamed A., et al.
Publicado: (2014)

The Association of eNOS Gene Polymorphism with Avascular Necrosis of Femoral Head
por: Zheng, Liwen, et al.
Publicado: (2014)

Insights into human eNOS, nNOS and iNOS structures and medicinal indications from statistical analyses of their interactions with bound compounds
por: Dong, Jianshu, et al.
Publicado: (2023)

Microtomographic, histomorphometric, and molecular features show a normal alveolar bone healing process in iNOS-deficient mice along a compensatory upregulation of eNOS and nNOS isoforms
por: FRANCISCONI, Carolina Fávaro, et al.
Publicado: (2023)

Dual-Specificity Phosphatase 4 Overexpression in Cells Prevents Hypoxia/Reoxygenation-Induced Apoptosis via the Upregulation of eNOS
por: Dougherty, Julie A., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ulskksfa6cvq3k4t5b812s5nch