Disruption of MEF2C signaling and loss of sarcomeric and mitochondrial integrity in cancer-induced skeletal muscle wasting

Cancer cachexia is a highly debilitating paraneoplastic disease observed in more than 50% of patients with advanced cancers and directly contributes to 20% of cancer deaths. Loss of skeletal muscle is a defining characteristic of patients with cancer cachexia and is associated with poor survival. Th...

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Detalles Bibliográficos
Autores principales: Shum, Angie M. Y., Mahendradatta, Theodore, Taylor, Ryland J., Painter, Arran B., Moore, Melissa M., Tsoli, Maria, Tan, Timothy C., Clarke, Stephen J., Robertson, Graham R., Polly, Patsie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314175/
https://www.ncbi.nlm.nih.gov/pubmed/22361433

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