On-line electrochemistry–bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors

In this study, an integrated approach is developed for the formation, identification and biological characterization of electrochemical conversion products of p38α mitogen-activated protein kinase inhibitors. This work demonstrates the hyphenation of an electrochemical reaction cell with a continuou...

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Detalles Bibliográficos
Autores principales: Falck, David, de Vlieger, Jon S. B., Giera, Martin, Honing, Maarten, Irth, Hubertus, Niessen, Wilfried M. A., Kool, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314180/
https://www.ncbi.nlm.nih.gov/pubmed/22227812
http://dx.doi.org/10.1007/s00216-011-5663-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314180/
https://www.ncbi.nlm.nih.gov/pubmed/22227812
http://dx.doi.org/10.1007/s00216-011-5663-2

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