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APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

The amyloid precursor protein (APP) is part of a larger gene family, which has been found to form homo- or heterotypic complexes with its homologues, whereby the exact molecular mechanism and origin of dimer formation remains elusive. In order to assess the cellular location of dimerization, we have...

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Detalles Bibliográficos
Autores principales:	Isbert, Simone, Wagner, Katja, Eggert, Simone, Schweitzer, Andrea, Multhaup, Gerd, Weggen, Sascha, Kins, Stefan, Pietrzik, Claus U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SP Birkhäuser Verlag Basel 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314181/ https://www.ncbi.nlm.nih.gov/pubmed/22105709 http://dx.doi.org/10.1007/s00018-011-0882-4

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