Cargando…
Delayed administration of VEGF rescues spinal motor neurons from death with a short effective time frame in excitotoxic experimental models in vivo
VEGF (vascular endothelial growth factor) prevents neuronal death in different models of ALS (amyotrophic lateral sclerosis), but few studies have addressed the efficacy of VEGF to protect motor neurons after the onset of symptoms, a critical point when considering VEGF as a potential therapeutic ta...
Autores principales: | Tovar-y-Romo, Luis B, Tapia, Ricardo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Neurochemistry
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314302/ https://www.ncbi.nlm.nih.gov/pubmed/22369757 http://dx.doi.org/10.1042/AN20110057 |
Ejemplares similares
-
Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates
por: Netzahualcoyotzi, Citlalli, et al.
Publicado: (2015) -
Role of energy metabolic deficits and oxidative stress in excitotoxic spinal motor neuron degeneration in vivo
por: Santa-Cruz, Luz Diana, et al.
Publicado: (2014) -
Sodium butyrate does not protect spinal motor neurons from AMPA-induced excitotoxic degeneration in vivo
por: Prior-González, Mara, et al.
Publicado: (2023) -
Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism
por: Lazo-Gomez, Rafael, et al.
Publicado: (2017) -
Inducing Chronic Excitotoxicity in the Mouse Spinal Cord to Investigate Lower Motor Neuron Degeneration
por: Blizzard, Catherine A., et al.
Publicado: (2016)