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Preventing β-Cell Loss and Diabetes With Calcium Channel Blockers

Although loss of functional β-cell mass is a hallmark of diabetes, no treatment approaches that halt this process are currently available. We recently identified thioredoxin-interacting protein (TXNIP) as an attractive target in this regard. Glucose and diabetes upregulate β-cell TXNIP expression, a...

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Detalles Bibliográficos
Autores principales:	Xu, Guanlan, Chen, Junqin, Jing, Gu, Shalev, Anath
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314354/ https://www.ncbi.nlm.nih.gov/pubmed/22442301 http://dx.doi.org/10.2337/db11-0955

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