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Metformin Prevents the Development of Chronic Heart Failure in the SHHF Rat Model

Insulin resistance is a recently identified mechanism involved in the pathophysiology of chronic heart failure (CHF). We investigated the effects of two insulin-sensitizing drugs (metformin and rosiglitazone) in a genetic model of spontaneously hypertensive, insulin-resistant rats (SHHF). Thirty SHH...

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Detalles Bibliográficos
Autores principales:	Cittadini, Antonio, Napoli, Raffaele, Monti, Maria Gaia, Rea, Domenica, Longobardi, Salvatore, Netti, Paolo Antonio, Walser, Marion, Samà, Mariateresa, Aimaretti, Gianluca, Isgaard, Jörgen, Saccà, Luigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Pharmacology and Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314362/ https://www.ncbi.nlm.nih.gov/pubmed/22344560 http://dx.doi.org/10.2337/db11-1132

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