Characterization of the Proteostasis Roles of Glycerol Accumulation, Protein Degradation and Protein Synthesis during Osmotic Stress in C. elegans

Exposure of C. elegans to hypertonic stress-induced water loss causes rapid and widespread cellular protein damage. Survival in hypertonic environments depends critically on the ability of worm cells to detect and degrade misfolded and aggregated proteins. Acclimation of C. elegans to mild hypertoni...

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Detalles Bibliográficos
Autores principales: Burkewitz, Kristopher, Choe, Keith P., Choung-Hee Lee, Elaine, Deonarine, Andrew, Strange, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314593/
https://www.ncbi.nlm.nih.gov/pubmed/22470531
http://dx.doi.org/10.1371/journal.pone.0034153

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