Cargando…

Methamphetamine Causes Differential Alterations in Gene Expression and Patterns of Histone Acetylation/Hypoacetylation in the Rat Nucleus Accumbens

Methamphetamine (METH) addiction is associated with several neuropsychiatric symptoms. Little is known about the effects of METH on gene expression and epigenetic modifications in the rat nucleus accumbens (NAC). Our study investigated the effects of a non-toxic METH injection (20 mg/kg) on gene exp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martin, Tracey A., Jayanthi, Subramaniam, McCoy, Michael T., Brannock, Christie, Ladenheim, Bruce, Garrett, Tiffany, Lehrmann, Elin, Becker, Kevin G., Cadet, Jean Lud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314616/ https://www.ncbi.nlm.nih.gov/pubmed/22470541 http://dx.doi.org/10.1371/journal.pone.0034236

Ejemplares similares

Enhanced Upregulation of CRH mRNA Expression in the Nucleus Accumbens of Male Rats after a Second Injection of Methamphetamine Given Thirty Days Later
por: Cadet, Jean Lud, et al.
Publicado: (2014)

Compulsive methamphetamine taking in the presence of punishment is associated with increased oxytocin expression in the nucleus accumbens of rats
por: Krasnova, Irina N., et al.
Publicado: (2017)

CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens
por: Torres, Oscar V., et al.
Publicado: (2015)

Increased expression of proenkephalin and prodynorphin mRNAs in the nucleus accumbens of compulsive methamphetamine taking rats
por: Cadet, Jean Lud, et al.
Publicado: (2016)

Methamphetamine Induces TET1- and TET3-Dependent DNA Hydroxymethylation of Crh and Avp Genes in the Rat Nucleus Accumbens
por: Jayanthi, Subramaniam, et al.
Publicado: (2017)

Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum
por: Cadet, Jean Lud, et al.
Publicado: (2013)

A Single Prior Injection of Methamphetamine Enhances Methamphetamine Self-Administration (SA) and Blocks SA-Induced Changes in DNA Methylation and mRNA Expression of Potassium Channels in the Rat Nucleus Accumbens
por: Jayanthi, Subramaniam, et al.
Publicado: (2019)

Methamphetamine-Induced Dopamine-Independent Alterations in Striatal Gene Expression in the 6-Hydroxydopamine Hemiparkinsonian Rats
por: Cadet, Jean Lud, et al.
Publicado: (2010)

Footshock-Induced Abstinence from Compulsive Methamphetamine Self-administration in Rat Model Is Accompanied by Increased Hippocampal Expression of Cannabinoid Receptors (CB1 and CB2)
por: Jayanthi, Subramaniam, et al.
Publicado: (2022)

Transcriptional and Epigenetic Substrates of Methamphetamine Addiction and Withdrawal: Evidence from a Long-Access Self-Administration Model in the Rat
por: Cadet, Jean Lud, et al.
Publicado: (2014)

Epigenetic Regulatory Dynamics in Models of Methamphetamine-Use Disorder
por: Jayanthi, Subramaniam, et al.
Publicado: (2021)

Biochemical Neuroadaptations in the Rat Striatal Dopaminergic System after Prolonged Exposure to Methamphetamine Self-Administration
por: Jayanthi, Subramaniam, et al.
Publicado: (2022)

Methamphetamine Induces Dopamine D1 Receptor-Dependent Endoplasmic Reticulum Stress-Related Molecular Events in the Rat Striatum
por: Jayanthi, Subramaniam, et al.
Publicado: (2009)

Compulsive methamphetamine self-administration in the presence of adverse consequences is associated with increased hippocampal mRNA expression of cellular adhesion molecules
por: Munoz, Ceiveon, et al.
Publicado: (2023)

Involvement of Dopamine Receptors in Binge Methamphetamine-Induced Activation of Endoplasmic Reticulum and Mitochondrial Stress Pathways
por: Beauvais, Genevieve, et al.
Publicado: (2011)

Epigenetic Landscape of Methamphetamine Use Disorder
por: Cadet, Jean Lud, et al.
Publicado: (2021)

Methamphetamine Self-Administration Is Associated with Persistent Biochemical Alterations in Striatal and Cortical Dopaminergic Terminals in the Rat
por: Krasnova, Irina N., et al.
Publicado: (2010)

Selective Activation of Striatal NGF-TrkA/p75NTR/MAPK Intracellular Signaling in Rats That Show Suppression of Methamphetamine Intake 30 Days following Drug Abstinence
por: Torres, Oscar V, et al.
Publicado: (2017)

Epigenetic landscape of amphetamine and methamphetamine addiction in rodents
por: Godino, Arthur, et al.
Publicado: (2015)

Potassium Channels and Their Potential Roles in Substance Use Disorders
por: McCoy, Michael T., et al.
Publicado: (2021)

Methamphetamine Preconditioning Alters Midbrain Transcriptional Responses to Methamphetamine-Induced Injury in the Rat Striatum
por: Cadet, Jean Lud, et al.
Publicado: (2009)

Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: Potential therapeutic impacts
por: Daiwile, Atul P., et al.
Publicado: (2022)

Sex-Specific Alterations in Dopamine Metabolism in the Brain after Methamphetamine Self-Administration
por: Daiwile, Atul P., et al.
Publicado: (2022)

Long-Term Protective Effects of Methamphetamine Preconditioning Against Single-Day Methamphetamine Toxic Challenges
por: Hodges, A.B, et al.
Publicado: (2011)

Escalated Oxycodone Self-Administration and Punishment: Differential Expression of Opioid Receptors and Immediate Early Genes in the Rat Dorsal Striatum and Prefrontal Cortex
por: Blackwood, Christopher A., et al.
Publicado: (2020)

Oxycodone self-administration activates the mitogen-activated protein kinase/ mitogen- and stress-activated protein kinase (MAPK-MSK) signaling pathway in the rat dorsal striatum
por: Blackwood, Christopher A., et al.
Publicado: (2021)

Molecular Adaptations in the Rat Dorsal Striatum and Hippocampus Following Abstinence-Induced Incubation of Drug Seeking After Escalated Oxycodone Self-Administration
por: Blackwood, Christopher A., et al.
Publicado: (2018)

Chronic Methamphetamine Administration Causes Differential Regulation of Transcription Factors in the Rat Midbrain
por: Krasnova, Irina N., et al.
Publicado: (2011)

mRNA changes in nucleus accumbens related to methamphetamine addiction in mice
por: Zhu, Li, et al.
Publicado: (2016)

Methamphetamine leads to the alterations of microRNA profiles in the nucleus accumbens of rats
por: Yang, Jing, et al.
Publicado: (2020)

Common fragile sites are characterized by histone hypoacetylation
por: Jiang, Yanwen, et al.
Publicado: (2009)

Dysregulation of Acetylation Enzymes in Animal Models of Psychostimulant use Disorders: Evolving Stories
por: Cadet, Jean Lud
Publicado: (2016)

Alleviation of Methamphetamine Sensitization by Partially Lesioning Dopaminergic Terminals with 6-Hydroxydopamine in Nucleus Accumbens
por: Chen, Shu-Chun, et al.
Publicado: (2021)

Methamphetamine induces alterations in the long non-coding RNAs expression profile in the nucleus accumbens of the mouse
por: Zhu, Li, et al.
Publicado: (2015)

Repeated methamphetamine treatment increases spine density in the nucleus accumbens of serotonin transporter knockout mice
por: Kasahara, Yoshiyuki, et al.
Publicado: (2019)

Different roles of Rac1 in the acquisition and extinction of methamphetamine-associated contextual memory in the nucleus accumbens
por: Zhao, Jinlan, et al.
Publicado: (2019)

Maternal Methamphetamine Exposure Influences Behavioral Sensitization and Nucleus Accumbens DNA Methylation in Subsequent Generation
por: Dong, Nan, et al.
Publicado: (2022)

Persistent Neuroadaptations in the Nucleus Accumbens Core Accompany Incubation of Methamphetamine Craving in Male and Female Rats
por: Funke, Jonathan R., et al.
Publicado: (2023)

Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin
por: Casas-Delucchi, Corella S., et al.
Publicado: (2012)

The effect of self-administered methamphetamine on GABAergic interneuron populations and functional connectivity of the nucleus accumbens and prefrontal cortex
por: Robinson, Katherine J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3c4c166qvnaekulnm6vjp655oq