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Insect Neuropeptide Bursicon Homodimers Induce Innate Immune and Stress Genes during Molting by Activating the NF-κB Transcription Factor Relish

BACKGROUND: Bursicon is a heterodimer neuropeptide composed of two cystine knot proteins, bursicon α (burs α) and bursicon β (burs β), that elicits cuticle tanning (melanization and sclerotization) through the Drosophila leucine-rich repeats-containing G protein-coupled receptor 2 (DLGR2). Recent st...

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Detalles Bibliográficos
Autores principales: An, Shiheng, Dong, Shengzhang, Wang, Qian, Li, Sheng, Gilbert, Lawrence I., Stanley, David, Song, Qisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314635/
https://www.ncbi.nlm.nih.gov/pubmed/22470576
http://dx.doi.org/10.1371/journal.pone.0034510