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Human Embryonic Stem Cells Differentiated to Lung Lineage-Specific Cells Ameliorate Pulmonary Fibrosis in a Xenograft Transplant Mouse Model
BACKGROUND: Our aim was to differentiate human (h) embryonic stem (ES) cells into lung epithelial lineage-specific cells [i.e., alveolar epithelial type I (AEI) and type II (AEII) cells and Clara cells] as the first step in the development of cell-based strategies to repair lung injury in the bleomy...
Autores principales: | Banerjee, Ena Ray, Laflamme, Michael A., Papayannopoulou, Thalia, Kahn, Michael, Murry, Charles E., Henderson, William R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314647/ https://www.ncbi.nlm.nih.gov/pubmed/22470441 http://dx.doi.org/10.1371/journal.pone.0033165 |
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