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Chemoinformatic Identification of Novel Inhibitors against Mycobacterium tuberculosis L-aspartate α-decarboxylase

L-Aspartate α-decarboxylase (ADC) belongs to a class of pyruvoyl dependent enzymes and catalyzes the conversion of aspartate to β-alanine in the pantothenate pathway, which is critical for the growth of several micro-organisms, including Mycobacterium tuberculosis (Mtb). Its presence only in micro-o...

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Detalles Bibliográficos
Autores principales:	Sharma, Reetu, Kothapalli, Roopa, Van Dongen, Antonius M. J., Swaminathan, Kunchithapadam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314653/ https://www.ncbi.nlm.nih.gov/pubmed/22470451 http://dx.doi.org/10.1371/journal.pone.0033521

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