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Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice

Tamoxifen (Tm)-inducible Cre recombinases are widely used to perform gene inactivation and lineage tracing studies in mice. Although the efficiency of inducible Cre-loxP recombination can be easily evaluated with reporter strains, the precise length of time that Tm induces nuclear translocation of C...

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Detalles Bibliográficos
Autores principales:	Reinert, Rachel B., Kantz, Jeannelle, Misfeldt, Amanda Ackermann, Poffenberger, Greg, Gannon, Maureen, Brissova, Marcela, Powers, Alvin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314663/ https://www.ncbi.nlm.nih.gov/pubmed/22470452 http://dx.doi.org/10.1371/journal.pone.0033529

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