Amyloid Precursor Protein (APP) Mediated Regulation of Ganglioside Homeostasis Linking Alzheimer's Disease Pathology with Ganglioside Metabolism

Gangliosides are important players for controlling neuronal function and are directly involved in AD pathology. They are among the most potent stimulators of Aβ production, are enriched in amyloid plaques and bind amyloid beta (Aβ). However, the molecular mechanisms linking gangliosides with AD are...

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Detalles Bibliográficos
Autores principales: Grimm, Marcus O. W., Zinser, Eva G., Grösgen, Sven, Hundsdörfer, Benjamin, Rothhaar, Tatjana L., Burg, Verena K., Kaestner, Lars, Bayer, Thomas A., Lipp, Peter, Müller, Ulrike, Grimm, Heike S., Hartmann, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314703/
https://www.ncbi.nlm.nih.gov/pubmed/22470521
http://dx.doi.org/10.1371/journal.pone.0034095

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