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The Notch-Regulated Ankyrin Repeat Protein Is Required for Proper Anterior–Posterior Somite Patterning in Mice
The Notch-regulated ankyrin repeat protein (Nrarp) is a component of a negative feedback system that attenuates Notch pathway-mediated signaling. In vertebrates, the timing and spacing of formation of the mesodermal somites are controlled by a molecular oscillator termed the segmentation clock. Somi...
Autores principales: | Krebs, Luke T, Bradley, Cara K, Norton, Christine R, Xu, Jingxia, Oram, Kathleen F, Starling, Christa, Deftos, Michael L, Bevan, Michael J, Gridley, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314717/ https://www.ncbi.nlm.nih.gov/pubmed/21998026 http://dx.doi.org/10.1002/dvg.20813 |
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