Immunoglobulin A Nephropathy Associated with Plasmodium falciparum Malaria

Glomerulonephritis occurs as a rare form of renal manifestation in Plasmodium falciparum malaria. Herein, we report a case of falciparum malaria-associated IgA nephropathy for the first time. A 49-yr old male who had been to East Africa was diagnosed with Plasmodium falciparum malaria. Microhematuri...

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Detalles Bibliográficos
Autores principales: Yoo, Dong Eun, Kim, Jeong Ho, Kie, Jeong Hae, Park, Yoonseon, Chang, Tae Ik, Oh, Hyung Jung, Kim, Seung Jun, Yoo, Tae-Hyun, Choi, Kyu Hun, Kang, Shin-Wook, Han, Seung Hyeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314860/
https://www.ncbi.nlm.nih.gov/pubmed/22468111
http://dx.doi.org/10.3346/jkms.2012.27.4.446
Descripción
Sumario:Glomerulonephritis occurs as a rare form of renal manifestation in Plasmodium falciparum malaria. Herein, we report a case of falciparum malaria-associated IgA nephropathy for the first time. A 49-yr old male who had been to East Africa was diagnosed with Plasmodium falciparum malaria. Microhematuria and proteinuria along with acute kidney injury developed during the course of the disease. Kidney biopsy showed mesangial proliferation and IgA deposits with tubulointerstitial inflammation. Laboratory tests after recovery from malaria showed disappearance of urinary abnormalities and normalization of kidney function. Our findings suggest that malaria infection might be associated with IgA nephropathy.

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