Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: Indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases

We have explored the possible role of dual specificity phosphatases (DUSPs) on acute EGF-mediated ERK signalling using high content imaging and a delayed MEK inhibition protocol to distinguish direct and indirect effects of the phosphatases on ERK activity. Using siRNAs, we were unable to find evide...

Descripción completa

Detalles Bibliográficos
Autores principales: Finch, Ann R., Caunt, Christopher J., Perrett, Rebecca M., Tsaneva-Atanasova, Krasimira, McArdle, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314959/
https://www.ncbi.nlm.nih.gov/pubmed/22245064
http://dx.doi.org/10.1016/j.cellsig.2011.12.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314959/
https://www.ncbi.nlm.nih.gov/pubmed/22245064
http://dx.doi.org/10.1016/j.cellsig.2011.12.021

Ejemplares similares